At the stroke of midnight on August 15, 1947, as India proclaims independence from Great Britain, two newborn babies are switched by a nurse in a Bombay hospital. Saleem Sinai, the illegitimate son of a poor woman, and Shiva, the offspring of a wealthy couple, are fated to live the destiny meant for each other. Their lives become mysteriously intertwined and are inextricably linked to India's whirlwind journey of triumphs and disasters.